Hyaluronic acid (HA) injections are a treatment method known as viscosupplementation, which is used to manage symptoms of knee osteoarthritis (OA) . The primary goals of this treatment are to reduce pain, improve joint movement by increasing lubrication, decrease friction and inflammation, and potentially slow the progression of OA .
The long-term effects of HA (sodium hyaluronate) injections for knee arthritis are generally positive, providing lasting pain relief and improved joint function. HA injections are safe and effective for osteoarthritis (including knee arthritis), relieving pain, maintaining and improving joint function, and reducing the use of oral analgesics. For elderly patients or those with specific medical histories, the use of HA can also reduce the adverse reactions that may be caused by other drugs.
In addition, although the effect of HA injections is slow to take effect, the pain relief can last for several months. Studies have shown that the improvement in pain ranges from 11% to 54% 5 to 13 weeks after HA injection. Compared with steroid hormones and oral analgesics, HA injections are slow to take effect, but their efficacy lasts longer.
Regarding the issue of dependence, there is no evidence that HA will cause dependence as a treatment. HA injection treatment mainly improves the properties of pathological joint fluid by supplementing exogenous HA, and there is no problem of addiction or dependence. However, when patients receive HA treatment, they should decide whether to repeat the treatment based on the progression of the disease, and the treatment can usually be repeated as needed after 6 to 12 months.
It is worth noting that the adverse reactions of HA injection treatment are usually mild, such as mild or moderate pain and swelling at the injection site. In most cases, patients can tolerate it without special treatment, and these symptoms will disappear after 2 to 3 days. Therefore, HA injection treatment of knee arthritis can be regarded as a safe and long-term treatment option.
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FAQ
Q: What are the side effects of HA injections for knee arthritis? How to prevent and treat them?
A: Side effects of HA injections for knee arthritis usually include local pain, swelling, joint edema, and occasionally headache, fever, and drug rash.
Q: What are the indications for HA injections in the treatment of knee arthritis?
A: The indications for HA injections to treat knee arthritis mainly include patients with mild to moderate osteoarthritis, especially when the secretion of synovial fluid decreases or the function degenerates, resulting in insufficient joint lubrication. It is suitable to supplement lubrication by injecting HA into the joint cavity. In addition, HA treatment is suitable for osteoarthritis of large joints, including the knee, ankle, hip, shoulder, elbow and wrist, especially for patients with mild to moderate osteoarthritis. HA is also recommended as a treatment option for patients who have undergone arthroscopic joint cleaning for OA.
Q: How effective is HA injection in treating knee arthritis? How many treatments are usually needed to see results?
A: Generally speaking, HA injections for the treatment of knee osteoarthritis may be relatively slow to take effect, but once they take effect, their effects are more lasting. A multicenter, randomized, placebo-controlled study conducted by the Spanish AMELIA research group pointed out that multiple courses of intra-articular injections of sodium hyaluronate for the treatment of knee osteoarthritis have a slow onset but lasting effect. Treatment usually requires a course of treatment, including injections once a week for 3 to 5 consecutive weeks, to achieve the best effect. In some cases, if the condition requires and is suitable for HA treatment, the treatment can be repeated after 6 to 12 months.
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