Methods For Distinguishing True And False Hyaluronic Acid

There are generally five kinds of micro-shape injection filling materials that are easily confused with hyaluronic acid on the market, including: omedine (or Ingelfal), silicone oil, paraffin oil, cellulose and collagen. There is a simple way to identify omedine - some of the "hyaluronic acid" containing omedine are mostly sold in beauty salons and some unqualified plastic surgeons bring them to the beauty salon to inject the guests in the beauty salon, one is injected in the beauty salon, and the temporal part is swollen after the injection, which is the expression of omedine. The street is full of fake hyaluronic acid and collagen, The illegal elements won the favor of some beauty seekers with low consumption ability at low prices, and were cheated, so they need to be well identified.
Identification steps:
Step 1: Squeeze a drop of colloidal material from the needle tube and place it on a white paper. If there is oil infiltration and diffusion, then this thing must not be hyaluronic acid, it must be silicone oil, or paraffin oil and other things. This material is clearly prohibited by law.
Step 2: If it is the diffusion of water infiltration halo, it may be hyaluronic acid, omedine (or Ingelfal), cellulose or collagen. At this time, further identification is needed! The identification method is to take a drop of hyaluronic acid and put it on the left palm, and then touch it repeatedly with the right index finger pulp. After a few minutes, after most of the water has evaporated, it can be seen through finger touch or naked eye observation that there are sand-like crystal particles in the remaining residue. There is nothing else, that is, cross-linked hyaluronic acid, which can basically be confirmed as real hyaluronic acid and can be used.
The third identification method: put the extruded product on the flat glass plate and observe it the next day. As a result, after overnight evaporation of water, the residual organic components on the glass plate were analyzed. If these residues are formed components, like "ice sand" particles piled up, it must be hyaluronic acid. If it is "pot like opaque scab, it is usually omedine; if it is a soft light yellow soft film, it is usually cellulose. If it is non-volatile oil, it must be silicone oil or paraffin oil. If nothing is left, it is likely to be non-crosslinked hyaluronic acid!
The fourth identification method: you can use the enzymatic hydrolysis method to identify whether the solid component is hyaluronic acid. The procedure is: put solid particles into a container containing hyaluronidase in a 45 ℃ thermostatic water bath, and the solid particles can be degraded in about 2 hours. If it is not degraded, it is definitely not hyaluronic acid. (This is bean curd with brine, one thing reduces one thing! The corresponding enzyme dissolves the corresponding compound)
Through the above methods, no one can fool you! Identify the cross-linked hyaluronic acid, whether it is true or not, you are an expert!